Epigenetics and Personalized Medicine

Two of the latest hot topics in lthe life sciences come together  in one workshop on Friday in the Calgary Technologies building where Genome Alberta calls home. Epigenetics is obviously a hot topic these days because it did after all make the cover of Time Magazine earlier this year. Personalized medicine makes its way into everything from government health care debates to the MIT Tecnhology Review. We're bringing together some pretty good people in the field as a first step in an epigenetics network in Alberta with the ultimate objective of building a complete epigenetics research strategy.

Epigenetics is the study of changes in appearance or gene expression caused by factors other than changes to the underlying DNA in an organism. As the Time Magazine article pointed out , it kind of messes with what many of us thought we had learned about nature and nurture. New research however says there are changes that can happen and be passed down through generations.

Here is the agenda for the morning:

Time Epigenetics Cover


  9:00a        Welcome and Introductions   (Bob Church)
  9:05a        Genome Alberta's Role   (David Bailey)
  9:20a        Personalized Medicine - It's Role in Alberta    (Marvin Fritzler)
  9:40a        A Computational Environment for the Characterization of Epigenetic Phenomena   (Christoph Sensen)

  10:00a      Break

  10:20a      Molecular Biomarkers in Personalized Medicine: A Public Health Perspective   (Alaa Badawi)
  10:40a      Circulating Nucelic Acids as Biomarkers in Disease Detection and Treartment in Animals and Humans      (Howard  Urnovitz)
  11:00a      Maternal and Child Health Genomics Initiative for Alberta and Canada   (Brent Scott)
  11:20a      Next Steps (Ted Bilyea)


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PrP New Media Follow up

We had a few technical problems at the New Media session today so here is some of what I promised I'd post.
Check my blog posting from earlier this week for links to what Colin Anderson, Stephane McLachlan, and Valerie Sim have been up to.
The video that did not work today is often referred to as Socialnomics or Social Media Revolution. Seems to depend on where you get the link from but here it is:



You are also free to download my presentation on slideshare at http://www.slideshare.net/mspear but here it is if you just wanted to look at it again. Check back later for some more links once I've got caught up. Enjoyed the session today and look forward to seeing what everyone has planned.



Canada's Prion Research Conference

Ah the elusive Prion. The folded protein behind BSE, CJD, Chronic Wasting disease, and playing a role in Alzheimer's, Parkinson's, and ALS.
And there you have it. My entire knowledge base (well almost), though when I was the  Marketing and Communications Manager for Alberta Beef Producers I was a litte more up on the latest developments. I'm a bit rusty these days, which is eactly why I'm in the Prion 101 workshop at the Prion Research Conference in Ottawa. Time to brush up.
The session is being run by Dr. Scott Napper, is an Associate Profesor at the University  of Saskatchewan as well as the Program Manager of Emerging Diseases at the Vaccine and Infectious Disease Organization. Prions lead to a novel form of infectious disease that results from the misfolding of a normal cellular protein. Dr. Napper likened it to a kind of molecular peer pressure because the proteins cause other proteins to do the same thing resulting in a cascading effect to the disease.  One of the challenges is that what we do know about prions does not account for all the complexities we see and it would appear that there is a LOT that we don't know about prions and related disease.
This conference while it may have answers, will likely raise a lot of questions with the 300 attendees from around the world.
So what's the Communications Director from Genome Alberta doing hanging out with a bunch of Prion researchers?
New media, what else.

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Drum Roll Please

We didn't break any records for entries to our 'Where Bio Began For Me' video contest but that doesn't matter, we're happy with the exposure we did get.
We've come into contact with some interesting people over the last few weeks, raised the profile of our GenOmics application and our blog, and we have some new video content linked to us on YouTube.

And of course we have winners:
Christopher Dieni from Penn State and Mostafa Abdellateef from the Genome Canada Bioinformatics Platform.

They win the iPod Shuffle and we'll be in touch with them soon to arrange delivery of these tiny music machines.
It doesn't end there however, as we have more stuff to give away next week.

Imagining Science cover image

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Twitter Snips - March 1, 2010

Twitter: a series of chirps or the high-pitched sound a bird makes.
A birds use its chirps, cheeps, and tweets to warn of danger, scare off predators, find a mate, protect its territory and to identify itself and its friends.

While the online microblogging tool version of Twitter is often dismissed as silly tweets more in line with canary chatter, perhaps we can learn a little from our feather friends. Tweety-bird let us all know when he saw the putty-cat and the online Twitter world lets us tell each other when know when we see things that interest us and cross all interest lines. No question you'll find your share of nonsense and the spammers have already started to move in, but such is the online world wherever you happen to click.

Genome Alberta can be found on Twitter as @mikesgene and we follow, or are followed by a wide range of people and organizations. There is I Am Biotech, one of the communication arms of the Biotechnology Industry Organization (BIO) in Washington D.C, Linda Avey one of the founders of 23andMe, PrionGirl who is actually Valerie Sim prion researcher, and Christopher Dieni originally from Montreal, went to school in Ottawa, and is now a postdoc in State College, at Penn State, researching cancer biochemistry.
Not a bad pedigree for a bunch of Twits and the rest of the people we keep in touch through Twitter are no less impressive. They cover the range of interests and careers from the media, to politics, to public relations, to science and medicine.
Every 2 weeks we compile some of the 140 character posting we come across and give you a sample to take you from the lab bench to the online bench. These are just the tip of the iceberg so if you really want to see what lies underneath then sign on to http://twitter.com and follow @mikesgene


Follow mikesgene on Twitter

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What Canadian Biotech Can Learn from Where Bio Began

It began in early February with a Tweet pointing to wherebiobegins.com which turned out to be a site with a large countdown clock and not much more. From there we began to see more tweets, a Facebook page, a YouTube channel and eventually a blog. There were videos posted from people about how bio began and we even shared in some of the fun by holding our own mini contest. Deadline is Saturday midnight by the way so there is still time to enter. Details and rules on our home page at www.genomealberta.ca and you can win an iPOD Shuffle so it is worth your time to enter.


Where Bio Begins countdown capture

But no one knew who was behind the site and the catch phrase.
I was let in on the secret of the company behind the mystery early on, and today Sigma Aldrich unveiled its full Where Bio Begins website and the rest of the campaign. It appears to be a well thought out plan and on the social media side I'd call it a pretty good success in the biotech field. The United States has many examples of good social media success. Check out I Am Biotech, What Can Biotech Do for YouComprendia's San Diego network or the Research Blogging site, or the DNA Network which we feature on our GenOmics application.

What about Canada?



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PR and Journalism - Where the Twain Shall Meet

This posting is not about biotech or science communication, genomics, genetics or even about social media but every once in a while I need to step outside the intent of Mikenomics a bit. For this posting I will put my journalist's badge back on and dedicate it to journalists who are strong enough to stay in the profession or brave enough to apply their skills elsewhere.
It started while I was preparing my notes and slides to speak to a student PR group at the University of Calgary and got a  note on Twitter from @jgombita pointing me to several blog postings from Craig Pearce:

Ex-journalists should not be the boss of PR
PR people should not head the PR function
Journalists for PR boss? Don’t ask; its discrimination!

These are the most recent missives in an ongoing the debate about whether journalists are qualified to hold a PR or Communications job but they are the among the more well thought out postings. As an ex-journalist now up to my neck in communication and PR, I just HAVE to respond. I also have some genetic proof that I lean towards stubborness so maybe that comes into play.

A few of the comments to Craig Pearce's postings were spot on, much like this one from Craig Badings : "it all depends on the person. There are some PR people not fit to head a PR function as there are ex journalists. Likewise if you look around there is a good mix of very able people from both backgrounds doing a great job".

What is common to Craig Pearce's original posts and many of the comments however, seems to be an over-simplification of what journalists actually do. It would appear from some of the discussion that our role as a journalist is to push information on an unsuspecting public from the cozy comfort of a desk. While a journalist starting out writing copy may have that role, so to does a shiney new PR graduate. Different push, different desk, same role.

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